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剧集的故事主要发生在某个不定的历史年代，地点是虚构的邻近京城的下河县里的“清明酒家”。故事围绕精明能干的孙掌柜（谢园饰演），自命不凡的张郎，油滑机灵的刘三儿和孙掌柜嫁不出来的女儿如花展开，同时带入他们身边的形形色色的人物，如常常来“清明酒家”走动的下河县师爷苏东（游本昌饰演），时不时来传传小道消息的“退休干部”周员外。形形色色的人因为这样那样的原因和别人打着交道，因为情感、原则、利益、地位、风俗等说大不大说小不小的问题产生矛盾，产生笑话。日复一日，家长里短，意料之外，情理之中，折射出的却是人情冷暖，是是非非。小姐你忘了，咱们刚来的时候。自此，偌大的历史画卷逐渐铺现。以仁在医学所的浮沉及自立门户后的众多医疗事件为主线，不仅坂本龙马、胜海舟、绪方洪庵、新撰组等人物/组织悉数登场，仁更邂逅了与自己在现代的未婚妻样貌惊人相似的美丽花魁野风（中谷美纪 饰）。深感命运神奇的仁在试图将现代医疗技术引入江户的同时，也努力扭转着历史洪流中众人命定的走向。爱丽丝的声音清脆灵动，犹如大珠小珠落玉盘，很是悦耳动听，但是话的内容……实在是让陈启不知道该说什么好。云影又不住安慰张老太太，喂了她一颗安神镇定的丸药。A TCP connection is a quad, and a connection is uniquely determined by the source IP, the source port, the destination IP and the destination port. Therefore, if C wants to forge the packet from A to B, it should fill in the above-mentioned IP header and TCP header with the source IP, source port, target IP and target port. Here B is the server, IP and port are open, A is the target we want to attack, IP certainly knows, but the source port of A is not clear, because it may be randomly generated by A. Of course, if we can find out the rule of generating source port for common OS such as Windows and Linux, we can still do it. In addition, we can step on the connection port of Car A through a large number of controlled hosts.